abstract：:This research was designed to detect the function of low-density lipoprotein receptor (LDLR)-related protein 8 (LRP8) in breast cancer (BC). Our results revealed that LRP8 was highly expressed in BC tissues and cell lines compared with human normal breast tissues. The poor prognosis of patients with BC was associated ...

journal_title：Archives of physiology and biochemistry

authors： Li L,Qu WH,Ma HP,Wang LL,Zhang YB,Ma Y

更新日期：2020-01-29 00:00:00

abstract：:Context: Deleterious effects of diabetes on seminal quality, serum metals and antioxidants have been confirmed.Objective: This study evaluated the effect of combined calcium, magnesium, vitamin C and E supplementation on seminal parameters, serum total antioxidant capacity (TAC), nitric oxide (NO), malonyldialdehyde (...

journal_title：Archives of physiology and biochemistry

authors： Bassey IE,Ikpi DE,Isong IKP,Akpan UO,Onyeukwu CC,Nwankwo NP,Udofia IG

更新日期：2020-01-25 00:00:00

abstract：:Objective: The pattern of urinary excretion of total sulphated glycosaminoglycans (GAGs) and their particular types: chondroitin sulphate/dermatan sulphate (CS/DS) and heparan sulphate (HS) was analysed in obese patients with type 2 diabetes mellitus (T2DM) treated with metformin in monotherapy for the period of six m...

journal_title：Archives of physiology and biochemistry

authors： Jura-Półtorak A,Olczyk P,Chałas-Lipka A,Komosińska-Vassev K,Kuźnik-Trocha K,Winsz-Szczotka K,Ivanova D,Kiselova-Kaneva Y,Krysik K,Telega A,Olczyk K

更新日期：2019-12-09 00:00:00

abstract：:Aberrant expression of miRNAs has a link with tumorgenesis and their deregulation is reported in biological fluids of cancer patients. Authors aimed to investigate the diagnostic role of miRNA-17-5p, miR-155 and miRNA-222 in serum samples from breast cancer patients (n = 80), benign breast patients (n = 40) and health...

journal_title：Archives of physiology and biochemistry

authors： Swellam M,Zahran RFK,Abo El-Sadat Taha H,El-Khazragy N,Abdel-Malak C

更新日期：2019-12-01 00:00:00

abstract：:Objective: To evaluate the effect of the administration of phytoestrogens on obesity, type 2 diabetes, and liver-kidney toxicity. Methods: Phytoestrogens (phyto(E2)) were administrated to high fructose-fat diet (HFFD). Results: This study showed that administration of phyto(E2) to HFFD-mice inhibited lipase activity b...

journal_title：Archives of physiology and biochemistry

authors： Hamden K,Boujibiha MA,Ben Abdeljelil N,Njima M,Selmi B,Achour L

更新日期：2019-12-01 00:00:00

abstract：:Diabetes is associated with depression and anxiety symptoms. The current investigation was designed to explore the effect of melatonin on depressive and anxiety like-behaviours, oxidative stress, levels of AGE, RAGE and S100B in streptozotocin-induced diabetic rats. The animals were divided into four groups: Normoglyc...

journal_title：Archives of physiology and biochemistry

authors： Ergenc M,Ozacmak HS,Turan I,Ozacmak VH

更新日期：2019-11-15 00:00:00

abstract：:Objective: To evaluate the diagnostic and prognostic value of biomarkers and new bioscore in septic patients in intensive care unit (ICU).Materials and methods: A study was conducted on septic and non-septic patients in ICU. Diagnostic and prognostic values of C-reactive protein (CRP), procalcitonin (PCT), Sequential ...

journal_title：Archives of physiology and biochemistry

authors： Sen P,Demirdal T,Nemli SA,Sencan A

更新日期：2019-11-05 00:00:00

abstract：:Autophagy is an important life phenomenon in eukaryotic cells. Its main role is to remove and degrade its damaged organelles and excess biological macromolecules, and use degradation products to provide energy and rebuild the cell structure, playing an important role in maintaining cell homeostasis and cell life activ...

journal_title：Archives of physiology and biochemistry

authors： Xu HM,Hu F

更新日期：2019-10-09 00:00:00

abstract：:Objective: The present study aimed to investigate the effects of Juglans regia (JR) extract on hyperglycaemia and insulin sensitivity. Methods: Forty rats were divided into 4 groups: Control (C), Diabetes Control (DC), Diabetes + Juglans regia (D + JR) and Diabetes + Metformin (D + M). Results: In the D + JR group, Fa...

journal_title：Archives of physiology and biochemistry

authors： Atila Uslu G,Uslu H

更新日期：2019-09-23 00:00:00

abstract：:Serum uric acid is associated with an increased risk of hypertension, cardiovascular disease and chronic kidney disease. Hyperuricemia raises the risk of insulin resistance and metabolic syndrome including diabetes. Aim: To find the association between purine metabolites and diabetic complications in rats. Materials a...

journal_title：Archives of physiology and biochemistry

authors： Varadaiah YGC,Sivanesan S,Nayak SB,Thirumalarao KR

更新日期：2019-09-13 00:00:00

abstract：:Background: Adiponectin gene polymorphisms have recently been reported to be associated with obesity. In Egypt, obesity has expanded especially with the changing nourishment propensities and the inexorably inactive ways of life, with almost 70 percent of the Egyptian populations being obese. Aim: To assess the relatio...

journal_title：Archives of physiology and biochemistry

authors： Elghazy AM,Elsaeid AM,Refaat M,Youssef MM

更新日期：2019-09-10 00:00:00

abstract：:Context: Small peptides as multifunctional biomolecules can prevent the metabolic disorders such as diabetes. Objective: The purpose of this study was to investigate the effects of small peptides on the enzymes and histopathology of the liver in mice exposed to diabetes. Methods: Di- and tri-peptides containing prolin...

journal_title：Archives of physiology and biochemistry

authors： Mesgari-Abbasi M,Valizadeh H,Mirzakhani N,Vahdatpour T

更新日期：2019-09-09 00:00:00

abstract：:Type 2 diabetes mellitus (T2DM) is the most prevalent disease and becoming a serious public health threat worldwide. In recent years, numerous effective T2DM intervention regimens have been developed, with promising results. However, these regimens are not usually economically available, and they are not well tolerate...

journal_title：Archives of physiology and biochemistry

authors： El-Tantawy WH

更新日期：2019-09-02 00:00:00

abstract：:Background: We aim to identify and analyze the expression of dyregulated RNAs in colorectal cancer (CRC). Methods: We selected a panel of RNAs specific to CRC composed of Nucleosome Assembly Protein 1 Like 2 (NAP1L2) mRNA, LNCRNA SNHG14 small nucleolar RNA host gene 14 (LNCRNA SNHG14) and homo sapiens microRNA-3940-5p...

journal_title：Archives of physiology and biochemistry

authors： Matboli M,Shafei AE,Ali MA,El-Din Ahmed TS,Naser M,Abdel-Rahman T,Anber N,Ali M

更新日期：2019-08-09 00:00:00

abstract：:This study investigates the alcoholic extract effect of Alhagi camelorum on blood glucose and lipid profiles in diabetic rats made by streptozotocin (STZ). Male rats were divided into four groups. The control group received a normal diet. The diabetic group was induced by STZ and two diabetic experimental groups recei...

journal_title：Archives of physiology and biochemistry

authors： Nabiyouni F,Vaezi G,Malekirad AA

更新日期：2019-08-04 00:00:00

abstract：:Aim: This study designated to investigate and compare the therapeutic effect of Ulva lactuca methanolic extract against oxidative stress (OS)-infertility induced by naturally occurring prooxidants (gossypol) and selenium- vitamins A, C, and E (selenium-ACE) drug. Methods: Male infertility was induced in rat by intrape...

journal_title：Archives of physiology and biochemistry

authors： Ghareeb DA,Abd-Elgwad A,El-Guindy N,Yacout G,Zaatout HH

更新日期：2019-07-31 00:00:00

abstract：:To investigate the antidiabetic effect of isopulegol in high-fat diet (HFD)/streptozotocin (STZ)-induced diabetic rats. Animals were made diabetic by feeding HFD for 4 weeks followed by single intraperitoneal injection of STZ (35 mg/kg b.w.; 0.1 M citrate buffer; pH 4.0). Plasma insulin, haemoglobin and glycogen conte...

journal_title：Archives of physiology and biochemistry

authors： Kalaivani K,Sankaranarayanan C

更新日期：2019-07-10 00:00:00

abstract：:An accumulating body of evidence supports the role of autophagy in the pathophysiology of T2DM. Also, abnormal endoplasmic reticulum (ER) stress response that has been implicated as a cause of insulin resistance (IR) could also be affected by the autophagic status in β-cells. The present study was designed to investig...

journal_title：Archives of physiology and biochemistry

authors： Gadallah SH,Ghanem HM,Abdel-Ghaffar A,Metwaly FG,Hanafy LK,Ahmed EK

更新日期：2019-06-19 00:00:00

abstract：:Due to the importance of zinc as an antioxidant and its crucial role in insulin synthesis, its deficiency may affect adversely diabetic state. So, this study aimed to modulate these effects using Curcuma longa as natural antioxidant. Rats were divided into four groups: two groups fed a zinc sufficient diet one non-dia...

journal_title：Archives of physiology and biochemistry

authors： Tebboub I,Kechrid Z

更新日期：2019-06-19 00:00:00

abstract：:Diabetes represents an important public health problem. Recently, new molecular targets have been identified and exploited to treat this disease. Due to its pivotal role in glucose homeostasis, glucokinase (GCK) is a promising target for the development of novel antidiabetic drugs; however, pharmacological agents that...

journal_title：Archives of physiology and biochemistry

authors： Guzmán TJ,Gurrola-Díaz CM

更新日期：2019-06-18 00:00:00

abstract：:Introduction: There are few studies examining the effect of spinosad on cognitive functions in the literature. Methods: In this study, we applied spinosad 3 weeks in different doses to mice and examined their effects on antioxidant system and cognitive performance. Results: In the open field test, we observed a signif...

journal_title：Archives of physiology and biochemistry

authors： Acar A,Akkoc H,Erdinc M

更新日期：2019-06-07 00:00:00

abstract：:In this study, we report the synthesis of novel tris-chalcones and testing of human carbonic anhydrase I, and II isoenzymes (hCA I, and hCA II), acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and α-glycosidase (α-Gly) inhibitors for the development of novel chalcone structures towards for treatment of some...

journal_title：Archives of physiology and biochemistry

authors： Burmaoglu S,Yilmaz AO,Polat MF,Kaya R,Gulcin İ,Algul O

更新日期：2019-06-07 00:00:00

abstract：:Context: The anti-diabetic medicine metformin has been reported as an anti-ageing drug candidate as it mimics the benefits of caloric restriction and reduces ageing-related oxidative stress in various experimental organisms. Objective: We investigated the possible anti-oxidative role of metformin against rotenone-indu...

journal_title：Archives of physiology and biochemistry

authors： Tripathi SS,Singh AK,Akhtar F,Chaudhary A,Rizvi SI

更新日期：2019-06-01 00:00:00

abstract：:Spirulina platensis, is an alga rich in phycocyanin (potent antioxidant), is effective in regulating the balance of oxidative stress. The objective of this study is to observe the impact of ingestion of a highly oxidised vegetable oil, by rats of Wistar strain. Finally, we observe the effect of Spirulina used as an an...

journal_title：Archives of physiology and biochemistry

authors： Ould Amara-Leffad L,Ramdane H,Nekhoul K,Ouznadji A,Koceir EA

更新日期：2019-05-01 00:00:00

abstract：CONTEXT:Mechanisms by which ghrelin affords its cardioprotection in mammals remained unclear. OBJECTIVE:To examine if ghrelin confers cardio-protection during cardiac remodelling post-MI by modulating the RAF-1-MEK1/2-ERK1/2 signalling pathway. MATERIALS AND METHODS:Rats were divided into control, sham, sham + ghreli...

journal_title：Archives of physiology and biochemistry

authors： Eid RA,Alkhateeb MA,Al-Shraim M,Eleawa SM,Shatoor AS,El-Kott AF,Zaki MSA,Shatoor KA,Bin-Jaliah I,Al-Hashem FH

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:NAFLD patients have higher risk of atherosclerosis cardiovascular disease (ASCVD). apo B/apoA-I ratio and atherogenic index of plasma (AIP) have been suggested as biomarker for ASCVD. METHODS:apo A-I, apoB, aryl esterase (ARE) and paraoxonase (PON) activities and carotid intima media thickness (cIMT) were d...

journal_title：Archives of physiology and biochemistry

authors： Fadaei R,Meshkani R,Poustchi H,Fallah S,Moradi N,Panahi G,Merat S,Golmohammadi T

更新日期：2019-02-01 00:00:00

abstract：:Objective, materials and methods: The aim of this cross-sectional study with a consecutive enrolment was to analyse the role of high sensitive C-reactive protein (hs-CRP) measurement in similarly obese patients with and without the metabolic syndrome (MS). Results: In total, 589 obese patients were screened, of whom 1...

journal_title：Archives of physiology and biochemistry

authors： Kucharska A,Sawicka-Gutaj N,Owecki M

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:To determine the awareness of HbA1c values and correlate this with educational levels, dietary intake and physical activity in type II diabetic population of Trinidad. METHODS:Total of 222 type II diabetic subjects were assessed via questionnaire evaluating their demographics, type and duration of diabetes,...

journal_title：Archives of physiology and biochemistry

authors： Nayak BS,Khan K,Kidney C,Knowles V,Koo A,Lakhan A,Lalla D,Lalloo C,Lallo SA,Singh S

更新日期：2018-12-01 00:00:00

abstract：CONTEXT:The important role of exercise in pulmonary function during menopause is not well known. Oestrogen deficiency in ageing female mice is accompanied by increase in apoptotic markers such as caspase3 in the lung. OBJECTIVE:The present study was designed to investigate whether swimming training will ameliorate fib...

journal_title：Archives of physiology and biochemistry

authors： Daghigh F,Alihemmati A,Karimi P,Habibi P,Ahmadiasl N

更新日期：2018-10-01 00:00:00

abstract：:The present study aimed to evaluate the relationship between exercise and both l-tyrosine and oxidative stress using thiol/disulphide homeostasis via a novel biomarker in rats. Following the completion of the exercise and l-tyrosine protocol, serum total thiol, native thiol, and disulphide concentrations were determin...

journal_title：Archives of physiology and biochemistry

authors： Kayacan Y,Yazar H,Kisa EC,Ghojebeigloo BE

更新日期：2018-07-01 00:00:00

abstract：:The present study was designed to examine the preventive effects of camel milk (CM) against the toxic effects of acute exposure to carbon tetrachloride (CCl4) on the heart tissue of mice. Administration of a single dose of CCl4 caused cardio toxicity as monitored by an increase in lipid peroxidation (thiobarbituric ac...

journal_title：Archives of physiology and biochemistry

authors： Hamed H,Gargouri M,Bellassoued K,Ghannoudi Z,Elfeki A,Gargouri A

更新日期：2018-07-01 00:00:00

abstract：CONTEXT:Essential oils from Pinus species have been reported to have various therapeutic properties. OBJECTIVE:This study was undertaken to identify the chemical composition and cytoprotective effects of the essential oil of Pinus halepensis L. against aspirin-induced damage in cells in vitro. MATERIAL AND METHODS:Th...

journal_title：Archives of physiology and biochemistry

authors： Bouzenna H,Hfaiedh N,Bouaziz M,Giroux-Metges MA,Elfeki A,Talarmin H

更新日期：2017-12-01 00:00:00

abstract：CONTEXT:Vanillin is known to possess important antioxidant activity. OBJECTIVE:The current study was conducted to establish the therapeutic efficiency of vanillin against potassium bromate (KBrO3)-induced depression-like behavior and oxidative stress in mice. MATERIAL AND METHODS:Mice were exposed during 15 days eith...

journal_title：Archives of physiology and biochemistry

authors： Ben Saad H,Kharrat N,Driss D,Gargouri M,Marrakchi R,Jammoussi K,Magné C,Boudawara T,Ellouz Chaabouni S,Zeghal KM,Hakim A,Ben Amara I

更新日期：2017-07-01 00:00:00

abstract：:Cytotoxic effects, including oxidative stress, of low linear energy transfer (LET)-ionizing radiation are often underestimated and studies of their mechanisms using cell culture models are widely conducted with cells cultivated at atmospheric oxygen that does not match its physiological levels in body tissues. Also, c...

journal_title：Archives of physiology and biochemistry

authors： Džinić T,Hartwig S,Lehr S,Dencher NA

更新日期：2016-12-01 00:00:00

abstract：:Hepatotoxicity, induced by aluminium chloride (AlCl3), has been well studied but there are no reports about liver metallothionein (MT) genes induction. Therefore, it is of interest to establish the mechanism involving the relation between MT gene expression levels and the oxidative stress status in hepatic cells of al...

journal_title：Archives of physiology and biochemistry

authors： Ghorbel I,Chaabane M,Elwej A,Boudawara O,Abdelhedi S,Jamoussi K,Boudawara T,Zeghal N

更新日期：2016-10-01 00:00:00

abstract：:The roles of leptin, nesfatin-1 and kisspeptin in the regulation of food intake and/or reproduction are well known; however, the interactions between these hormones remain unclear, especially in humans. The aim of this study was to determine the roles of leptin, nesfatin-1 and kisspeptin in pre- and postmenopausal obe...

journal_title：Archives of physiology and biochemistry

authors： Çelik F,Belviranli M,Okudan N

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Insulin resistance (IR) is closely associated with increased atherogenic risk. OBJECTIVE:To investigate leptin, adiponectin, soluble intercellular adhesion molecule-1 (sICAM-1), soluble vascular cell adhesion molecule-1 (sVCAM-1) levels and their relationship with each other and metabolic parameters in wo...

journal_title：Archives of physiology and biochemistry

authors： Koleva DI,Orbetzova MM,Nikolova JG,Tyutyundzhiev SB

更新日期：2016-10-01 00:00:00

abstract：CONTEXT:Cardiometabolic disorders are rapidly becoming major public health challenges. Valproic acid (VPA) is a widely prescribed anticonvulsant drug. OBJECTIVE:We hypothesized that treatment with VPA would improve the regulation of glucose and atherogenic dyslipidemia through reduction in circulating corticosterone. ...

journal_title：Archives of physiology and biochemistry

authors： Olatunji LA,Omolekulo TE,Usman TO,Kim I

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:The potentially beneficial effects of pomegranate peel (PPE), flower (PFE) and seed oil (PSO) extracts, in comparison with rosiglitazone, on adiposity, lipid profile, glucose homoeostasis, as well as on the underlying inflammatory mechanisms, were examined in high-fat and high-sucrose (HF/HS) diet-induced obe...

journal_title：Archives of physiology and biochemistry

authors： Harzallah A,Hammami M,Kępczyńska MA,Hislop DC,Arch JR,Cawthorne MA,Zaibi MS

更新日期：2016-01-01 00:00:00

abstract：:The G0/G1 switch gene 2 (G0S2) protein attenuated adipose triglyceride lipase (ATGL) activity and decreased lipolysis in rodent and human adipocytes. We hypothesized that G0S2 mRNA expression in human adipose tissue is influenced by depot, adipocyte size, body weight and caloric intake. Adipose tissue samples were obt...

journal_title：Archives of physiology and biochemistry

authors： Skopp A,May M,Janke J,Kielstein H,Wunder R,Flade-Kuthe R,Kuthe A,Jordan J,Engeli S

更新日期：2016-01-01 00:00:00